Sensory abnormalities in unaffected relatives in familial adult-onset dystonia

O’Dwyer JP1, O’Riordan S1, Saunders-Pullman R3, Bressman SB3, Molloy F1, Lynch T2, Hutchinson M1

 

Neurology. 2005 Sep 27;65(6):938-40.

 

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1 Department of Neurology, St. Vincent’s University Hospital and University College Dublin.
2 Department of Neurology, Mater Misericordiae University Hospital.
3 Beth Israel Medical Center and Albert Einstein College of Medicine, New York, New York.

ABSTRACT:

Somatosensory abnormalities are found in adult-onset primary torsion dystonia (PTD). Therefore we assessed spatial discrimination thresholds (SDT), a measure of spatial acuity, in four multiplex families with adult-onset PTD. In family members aged 20 to 45 years vs controls (mean 2.5 SD), abnormal SDTs were found in four of five affected with adult-onset PTD and in 12 of 49 unaffected relatives. Sensory abnormalities

 

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Copyright © 2004 by AAN Enterprises, Inc.